In the late 1800s, disease in Chicago was rampant, as was common in the area at that time. One in six children died of diphtheria, cholera or dysentery, and the role of bacteria in disease transmission was still a new discovery. Although six medical schools were already in existence, five physician-educators: Charles Warrington Earle, Abraham Reeves Jackson, Daniel Atkinson King Steele, Samuel McWilliams and Leonard St. John—decided to open their own proprietary medical school. The gentlemen pooled together $5,541.78, purchased a piece of land and secured a certificate of incorporation. The new school, located on Harrison and Honore streets, was named the College of Physicians and Surgeons of Chicago (commonly referred to as P&S). Its doors opened on Sept. 26, 1882, with a class of 100 students and a faculty of 27 physicians.
At the West Side Free Dispensary, located on the first floor of the medical school, students in small groups could observe pathological cases and their treatment. Patients were classified according to the affected area or system of the body: heart, lungs, eyes, ears, skin or nervous system. The dispensary also furnished material for college clinics in medicine, surgery, gynecology, obstetrics, ophthalmology, neurology and pediatrics. In its first three years, the dispensary registered 20,353 patients and dispensed 17,347 prescriptions.