Jubilee Mission Hospital was established on 17 December 1951 as a small dispensary. In 1952, the hospital began its service with 4 rooms, 20 beds, 2 retired part-time doctors and 2 nurses of the Holy Cross Congregation. Under the leadership of Dr H.S. Adenwalla, the mission hospital grew to 1750 beds and is a major provider of health care services in Kerala.
Nursing school commenced in 1966 and the hospital was recognised by the Medical Council of India (MCI) in 1971 for internship training of doctors. Training of post graduate medical students for the National Board of Examinations commenced in 1990. In 2003, the MCI recognised the Jubilee Mission Hospital as a teaching hospital. The institution subsequently opened the Jubilee Medical College and the Jubilee School of Nursing
