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The Yong Loo Lin School of Medicine, established in 1905, is the first institution of higher learning in Singapore and the genesis of the National University of Singapore. The School is one of many who offer medical programmes in the Asia Pacific region. The Times Higher Education World University Rankings 2019 by subject and Quacquarelli Symonds (QS) World University Rankings by Subject 2019 list NUS Medicine as the leading medical school in Asia. Its distinguished alumni include cabinet ministers of Singapore, well-known doctors and a Prime Minister of Malaysia and father of the president-elect of Singapore.